Neuroscience Solutions

Nucleus has been designed to support the constantly evolving research in neuroscience. Accompanying you in your journey in the lab.

Forge ahead and advance your setup to a portable system that has the ability to reach 512 recording channels and record from one or multiple subjects simultaneously.

With the Nucleus, you have the ability to integrate electrical stimulation sources in the same box, while using the same software.

The rich I/O interface syncs with external devices while utilizing the I/O panel. This is done while using the open platform to build unique applications in a friendly environment.


Is it Suitable for me?

  • Recording with multiple subjects simultaneously
  • Complex setup with different sensors and actuator
  • Ephys set-up with simple electrical stimulation needs
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Up to 512 channels. Compact & portable data acquisition system with expandable channels.

Experiment Control: Embedded digital and analog input that allows connection to external sensors;

SDK enables access and control of sensors and actuator.

Headstage Ports: eight (8) ports

Digitized Headstages. Ultra-small and lightweight headstage suitable for all types of setups and subjects

Plug & Play System.  System ready to be used with variety of headstages (ex. Intan, Neuronexus, OpenEphys) and probes.

Built-in GUI. Modern, integrated and User-friendly software, with a customizable workspace that has the ability to control 3rd party systems.

Closed Loop. Use only one type of software to control all channel modes and enable closed-loop actions with short latency timing. (7ms)

Powerful DSPs. State-of-the-art Octa-core DSPs.

Software Development Kit Tool. SDK for two-way communication using MATLAB, Phyton, C# or C++ for streaming all data and control system functionality.

Electrical Safety and EMC design: The system was designed according to medical and electrical EMC testing to ensure medical compliance for the system in the future.


Complete Control & Data Access using Alpha Omega SDK

  • Data streaming. All data collected by the AlphaRS can be accessed online in MATLAB, Python, C# & C++.
  • Full system control. From within MATLAB, commands can be sent to adjust almost all system parameters or trigger unique stimulation paradigms.
  • Closed-loop functionality. Data can be analyzed online, and results can directly trigger digital outputs or stimulation
  • Easy programming. Specially designed MATLAB toolbox and instructions make accessing data in MATLAB simple and easy
  • Endless possibilities. Online access to data means each user can code paradigms specifically for their unique needs
  • Integrate with third-party software systems
  • Customize the User-Interface per your preferences
  • Flexible scope to use the software for writing new functions in one of the programming languages: MATLAB, Python, #C, C++
  • Adaptability. Editing functionality of specific features that are tailored to your needs


We offer a variety of digitizing Headstages with ultra-small sizes and weights suitable for a wide range of subjects and setups.
Out headstages can record all types of signals, and have integrated stimulation sources and sensors

  • Nucleus System can support up to 8 headstages
  • Supporting all types of brain signals: MER / EEG / EMG / ECOG / AKG
  • Various headstage configurations:
  • 16 channel headstages with 18pin Omnetics connector
  • 32 channel headstages with 36pin Omnetics connector
  • 64 channel headstages with 2x 36pimn Omnetics connector
  • Integrated stimulation
  • Low noise 2.4µV RMS
  • integrated 3-axis accelerometer sensor
  • Built-in impedance check
  • Flexible cable length

HeadStage compatible electrodes

Our headstages are compatible with numerous commercially-available electrodes, for information contact us.

The headstage connector can be customized per order

 Headstage Specifications



Number of Electrode Physiological Inputs

From 1 to 512

Headstage Configurations

The nucleus system connects to a different type of headstages:

·       16CH recording

·       16CH recording with accelerometer

·       16CH EMG recording

·       16CH EMG recording with accelerometer

·       32CH recording

·       32CH recording with accelerometer

·       64CH recording

·       64CH recording with accelerometer

·       16CH recording and stimulation

·       32CH recording and stimulation

Input Connector

18-pin Omnetics (16 channels HS)

36-pin Omnetics (32 channels HS)

2x 36pin Omnetics (64 channels HS)

Hardware High Pass Filter

1 Hz is the default and it is controllable by the SW

Hardware Low Pass Filter

10 kHz is the default and it is controllable by the SW

Total Gain


Dynamic Input range

± 5mV

Input Type

Unipolar input (1 analog reference and 1 ground)

Note: EMG HS has bipolar input; each channel has it is own reference contact.

A/D Resolution

16 bits

Input Bit Resolution

152 nV

Sampling Rate at HS*

30,000 Samples per second

Input Referred Noise (RMS)

< 2.4μV @ ground

Stimulation Sources

Each channel has it is own stimulation source

Stimulation Pulse

0.03ms - DC

Stimulation amplitude

1uA - 2.55mA

Voltage compliance

± 9V

Stimulation frequency

DC to 1Khz