Neuroscience Solutions

The alphaRS platform has been designed to support the constantly evolving research in neuroscience. 
Accompanying you in your journey in the lab.

The ultimate electrophysiology system is fully customizable. The advanced system, with online and flexible filtering and built-in ready-to-use statistical tools has the option to add multiple stimulation sources.

Let’s build your system together, and adapt it in your lab environment with our expert representatives.

  • System can reach 1024 Channels 
  • Open Source open platform with user-friendly API ( Python, MATLAB, C++, C#)
  • Online and flexible filtering: Raw, Spike, LFP & Segmented
  • NeuroExplorer License
  • Online statistical tools: Spike raster, firing rate, PSTH, and evoked potential
  • Integrated electrical stimulation
  • High-level priority customer support accompanying your research
  • Designed to fit different setups; free moving, restrained, and head-fixed setups with various subject sizes.
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Up to 1024 channels

Compact & portable data acquisition system with expandable channels

Digitized Headstages

Ultra-small and lightweight headstage suitable for all types of setups and subjects
Smallest 64 channels in the world (7*9 mm)

Server-based Software

Connecting to the network, allowing multiple-user to access the data online and control system functions

Plug & Play System

Use with a variety of Headstages including Intan, Neuronexus, OpenEphys, and more

Integrated Recording & Stimulation

Use only one type of software to control all channel modes and enable closed-loop actions with short latency timing

Real-time closed-loop/BMI/BCI

With less than 1.5 msec (>1.5msec) Data can be analyzed online, and results can directly trigger digital outputs or stimulation.

 

Up to 1024 channels. Compact & portable data acquisition system with expandable channels

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Open source and server based SW. alphaRS Pro has the ability to connect to the network, allowing simultaneous multiple-user to access the data online and control all system functions.

Online data streaming and full system control. User-friendly API for two-way communication using MATLAB, Phyton, C#, or C++ for streaming all data and control system functionality.

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Integrated Stimulation: Integrated electrical stimulation, all contacts can record and/or stimulate. Mode of the contact (recording or stimulation) can be controlled by the system’s API or user interface. 
- Use only one software and one hardware to control your neuromodulation experiments!

Impedance check: Built-in impedance check for all contacts, allowing the user by one click to check the electrode’s impedance during any stage of the experiment.

Closed Loop/BMI/BCI support. Low latency C++ API specially designed for advanced uses (BMI/BCI/Closed-loop experiments). Our C++ API runs under Windows OS and it can reach 1.5mS closed loop.

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Digitized Headstages. Ultra-small and lightweight headstage suitable for all types of setups and subjects.

Analog/Digital inputs and outputs: Embedded digital and analog input that allows connection to external sensors; SDK enables access and control of sensors and actuators 

Online Statistics: Spike raster, firing rate, PSTH, and evoked potential.

Online & Flexible Filtering: Real-time streaming of 4 signal types for each contact –> RAW, Spikes, LFP's & Segmented spikes.

User friendly GUI. Modern and User-friendly graphic user interface, with a customizable workspace and the ability to control 3rd party systems. Displayed different groups of channels with different filters. GUI uses GPU to display up to 2K channels.

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Complete Control & Data Access using Alpha Omega SDK

  • Data streaming. All data collected by the AlphaRS can be accessed online in MATLAB, Python, C# & C++.
  • Full system control. From within MATLAB, commands can be sent to adjust almost all system parameters or trigger unique stimulation paradigms.
  • Rich API packages: 4 available API packages with the most common programming languages: MATLAB, Python, #C, C++20231107130233.880.png
  • Closed-loop functionality. Data can be analyzed online, and results can directly trigger digital outputs or stimulation20231107130359.913.png
  • Easy programming. Specially designed MATLAB/Python toolbox and instructions make accessing data in MATLAB/Python simple and easy
  • Endless possibilities. Online access to data means each user can code paradigms specifically for their unique needs

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Features

Specifications and Options

Data Acquisition System

1024 channels real-time Data Acquisition
Stimulation Up to 256 electrical sources, any channel can be automatically switched from recording mode to stimulating
Impedance   One-Click online impedance check for
all contacts 

SW Filtering

 4 Selectable software digital filtering per channel (0.02Hz to 10KHz)

API packages

Online data streaming and full system control by:
Python,MATLAB, C++,C#

General purpose digital outputs

16 digital outputs, Synchronization TTL output

General purpose analog outputs

8 analog outputs ± 5.0 V, 16-bit analog outputs

General purpose digital Inputs

8 digital input channels (TTLs)
16-bit digital input port

General purpose analog Input

8 analog inputs
16 bit-resolution and dynamic range of ±5V

PC interface

Thunderbolt port (20Gbps or 40Gbps)

Power supply

4-pin DC power connector (100-240 VAC, 50-60 Hz)

HeadStage connectivity

8 HeadStages with USB-C connectors, fully isolated ports

LED Indicators

Indicating general system’s state

System size

36 x 26 x 9 cm

PC Specs

 

 CPU

i9 – Base-Clock at least 2.6Ghz

 RAM

32GB 

 Disk

 512GB NVMe SSD
GPU Nvidia GPU, at-least GTX1650 
Interface ports

1x Thunderbolt port

 OS

 Window 10 pro

 

The headstage is an integral part of your experimental setup, the size, and spec can have a huge impact on the subject’s behavior, therefore affecting the end results.

Alpha Omega is offering the smallest headstages in the market starting from 7x9mm and weight just 0.25 grams. We offer a variety of Headstages for a wide range of subjects and setups.

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Our headstages can record all types of electrophysiology signals, and have integrated stimulation sources and sensors.

  • alphaRS Pro System can support up to 8 headstages
  • Supporting all types of brain signals: MER / EEG / EMG / ECoG / EOG / AKG
  • Various headstage configurations:
  • 16 channel headstages with 18pin Omnetics connector
  • 32 channel headstages with 36pin Omnetics connector
  • 64 channel headstages with 2x 36pimn Omnetics connector
  • Integrated stimulation
  • Low noise 2.3µV RMS
  • Integrated 3-axis accelerometer sensor
  • Built-in impedance check
  • Flexible cable length
  • Plug and play with most electrodes in market. Customizations and adapters are available upon request
  • 30,000 sampling rate for all channels 

HeadStage compatible electrodes

Our headstages are compatible with numerous commercially-available electrodes, for information contact us.

The headstage connector can be customized per order

 

Headstage Specification

Parameter

Value

Number of Electrode Physiological Inputs

From 1 to 1024

Headstage Configurations

AlphaRS Pro system connects to a different type of headstages:

·       16CH recording

·       16CH recording with accelerometer

·       16CH EMG recording

·       16CH EMG recording with accelerometer

·       32CH recording

·       32CH recording with accelerometer

·       64CH recording

·       64CH recording with accelerometer

·       128CH recording 

·       128CH recording with accelerometer

·       16CH recording and stimulation

·       32CH recording and stimulation

Input Connector

16CH headstage   -> 18-pin Omnetics
32CH headstage   -> 36-pin Omnetics 
64CH headstage   -> 2x 36-pin Omnetics  OR 2x 34pin Molex Connector
128CH headstage -> 4x 36-pin Omnetics OR 4x 34pin Molex Connector

Hardware High Pass Filter

1 Hz is the default and it is controllable by the SW (only if you have the matching licensing – Advanced)

Hardware Low Pass Filter

10 kHz is the default and it is controllable by the SW

Total Gain

192

Dynamic Input range

± 5mV

Input Type

Unipolar input (1 analog reference and 1 ground)

Note

EMG HS has bipolar input; each channel has it is own reference contact.

A/D Resolution

16 bits

Input Bit Resolution

152 nV

Sampling Rate at HS*

30,000 Samples per second

Input Referred Noise (RMS)

< 2.3μV @ ground

Stimulation Sources

Each channel has it is own stimulation source

Stimulation Pulse

0.03ms - DC

Stimulation amplitude

1uA - 2.55mA

Voltage compliance

± 7V OR ± 9V 

Stimulation frequency

DC to 1Khz

Impedance Check

Measured, calculated, and reported – Possible to check with different frequencies and different amplitudes

Headstage interface cable

The default is 2 meter; it can be customizable up to 6 meters